From: Dr. Betty Martini, D.Hum., Bettym19@mindspring.com
To: Jeffrey.MOON@efsa.europa.eu, foodadditives-efsa.europa.eu
Date: Mon, Oct 03, 2011 4:59 pm
Subject: Aspartame Review: EFSA's False Data on Aspartame Comes from the manufacturers
To Jeffrey Moon & Food Additives-EFSA
There is a flood of publicity over conflict of interest. One reason your defense can’t be taken seriously is that the material on your web site on aspartame was provided by the aspartame producers and is emphatically wrong. If you’re working from biased data how can you make an unbiased decision? EFSA’s web site states aspartame doesn't get in the blood stream and doesn’t accumulate. Nothing is further from the truth. Maybe that's why data wasn't included like Dr. Woodrow Monte's peer reviewed journal article, "Aspartame: Methanol and the Public Interest": http://www.mpwhi.com/aspartame_methanol_and_public_health.pdf Just because the aspartame industry writes it down doesn't make it true.
Under your FAG: "Aspartame itself does not enter the bloodstream nor does it accumulate in the body." Such a statement is an absolute boldfaced lie. You've received information before about this and ignored it.
Here is admission that aspartame gets in the blood stream by Ajinomoto. Aspartame, Physiology and Biochemistry, Marcel Dekker, Inc., New York, L.D. Stegink and L. J. Filer, Jr., l984 (Pro industry, Significantly Corporate Sponsored!!) Searle was original manufacturer, bought by Monsanto in l985
Page 161: TISSUE DISTRIBUTION OF ORALLY ADMINISTERED ISOTOPICALLY LABELED ASPARTAME IN THE RAT Yoshimasa Matsuzawa and Yuichi O'Hara, Life Science Laboratory, Central Research Laboratories, Ajinomoto Company, Inc. Yokohama, Japan.
Page 162: RESULTS: Phenylalanine Moiety: "The pattern of distribution of (U-14CPhe) aspartame following its oral administration was very similar to that of (U-14C) phenylalanine after 0.5, 2.6 and 24 hr and 7 days. Thirty minutes after administration of these compounds, very high levels of radioactivity were observed in the lumen of the stomach and upper small bowel. Significant uptake of radioactivity was observed in the pancreas, gastrointestinal mucosa, hair follicles, salivary gland and liver. Radioactivity was observed in the kidney, adrenal gland, bone marrow, spleen and eye. Some radiolabel was localized to the BRAIN, SPINAL CORD, (emphasis added) heart, thymus, lung and testes,
Ajinomoto will have a hard time rebutting this study since they did it. There is endless information on aspartame in the blood.
Even corporate - sponsored studies affirmed the matter. For example, one of 15 pivotal studies submitted to the FDA for approval of aspartame was a "52 Week Oral Toxicity Infant Monkey Study (SC-18862). This study orally dosed aspartame to seven infant Rhesus monkeys in work conducted at the University of Wisconsin Medical Center at Madison. Reported in l972. The study reported "All animals in the medium and high dosage groups exhibited seizure activity. Seizures were observed for the first time following 218 days of treatment. The seizures were of the grand mal type...One monkey, m38 of the high dose group, died after 300 days of treatment. The cause of death was not determined..." The study correlates brain seizures with high amounts of phenylalanine ingested by the monkeys. The study determined: "following the end of the experiment, medium and high dose monkeys were kept under observation for three months. No further convulsions were detected during this period." In other words, once the aspartame was withdrawn from the monkey's diets, the brain seizures ceased. Monsanto spokesperson Dr. Robert Moser said that aspartame does not enter the blood stream. This lie about aspartame not getting in the blood stream is always from the aspartame industry, not reality or fact. The data revealed by this "pivotal" study submitted to FDA renders false Moser's assertion that Aspartame does not enter the blood stream. Elevated levels of phenylalanine in the blood of monkeys fed medium and high levels of Aspartame prove that the compound is absorbed into the blood stream. The brain seizures followed. How could any agency claim a "pivotal " study in which all of the medium and high dose monkeys suffer brain seizures, confirm Aspartame's safety for humans?
Neurosurgeon Russell Blaylock, M.D. in Excitotoxins: The Taste That Kills explains that for every molecule of aspartame metabolized, a molecule of methanol was released into the blood stream. An EPA assessment of methanol says it "is considered a cumulative poison due to the low rate of excretion once it is absorbed" The absorbed methanol is then slowly converted to formaldehyde by alcohol dehydrogenase in the liver (DHHS 1993a, Liesivuori 1991). The formaldehyde is then converted to formic acid by aldehyde dehydrogenase in the liver, by formaldehyde dehydrogenase in the blood or through the tetrahydrofolic acid dependent, one-carbon pool (Liesivuori 1991). Methanol thus breaks down into formaldehyde and formic acid in the body. Journal of the Diabetic Assoc. of India, A Health Alert, Emerging Facts About Aspartame, Vol. No. 35, No. 4: l995, J. Barua, A. Bal.
Aspartame is a molecule composed of three components, aspartic acid, methanol and phenylalanine. H. J. Roberts, M.D., says in Aspartame (NutraSweet) Is It Safe?
Page 30: "After ingestion there is a rapid breakdown and absorption of aspartame within the upper gastrointestinal tract. This results in a prompt rise of the two amino acids in the bloodstream."
Page 32: "Influence of Method of Administration" Both phenylalanine and aspartame concentrations in the blood plasma are significantly higher when aspartame is given as a solution rather than in capsule form."
As to accumulation: you know this happens. Aspartame Ingestion Causes Formaldehyde Accumulation in the Body. Excerpt from: Trocho, C., et al., 1998. "Formaldehyde Derived From Dietary Aspartame binds to Tissue Components in vivo, "Life Sciences, Vol. 63, No. 5, pp. 337+, 1998.
"These are indeed extremely high levels for adducts of formaldehyde, a substance responsible for chronic deleterious effects that has also been considered carcinogenic."
"It is concluded that aspartame consumption may constitute a hazard because of its contribution to the formation of formaldehyde adducts."
" It was a very interesting paper, that demonstrates that formaldehyde formation from aspartame ingestion is very common and does indeed accumulate within the cell, reacting with cellular proteins (mostly enzymes) an DNA (both mitochondrial and nuclear). The fact that it accumulates with each dose, indicates grave consequences among those who consume diet drinks and foodstuffs on a daily basis." Neuroscientist, Russell Blaylock, M.D. When the Trocho Study was done it upset the aspartame industry to the point that they tried to assassinate Dr. Maria Alemany's character, when he is a hero for doing the study and showing the world how deadly aspartame even pre-embalms. Dr. H. J. Roberts being Jewish even remarked that in this religion embalming is forbidden, and Jews are being embalmed without their knowledge. In the medical text, Aspartame Disease: An Ignored Epidemic, http://www.sunsentpress.com by Dr. Roberts which you have, (1000 pages of symptoms and diseases, drug interactions, etc.) there is a page on pre-embalming.
I visited Dr. Alemany in Barcelona and he said to me aspartame will kill 200 million people! The aspartame industry got Tephly to rebut the Trocho Study but even Tephly finally confessed he used the wrong test. No way to get around the accumulation of formaldehyde in the body.
As to the Denmark study on 60,000 women, to reject such a study only means there is industry influence. Only industry wants to forbid a pregnancy warning. To not alert mothers their child could be born with autism or other birth defects is simply demonic. One never questions the signs many times in restaurants telling pregnant women they shouldn't drink alcohol isn't methanol or wood alcohol much worse? This is accepted medical science.
Dr. Russell Blaylock said: "What makes aspartame particularly dangerous is that it contains three neurotoxins. Methanol is a very powerful neurotoxin, in fact the EPA controls methanol exposure very carefully allowing only very minute levels to be found in foods or in environmental exposures. But, it's interesting that the level allowed in NutraSweet is seven (7) times the amount that the EPA will allow anyone else to use. So methanol is an extremely powerful neurotoxin. It can produce blindness, it can produce cellular destruction in the brain and spinal cord in particular the optic nerves that has to do with our vision. The second amino acid, aspartic acid of course is an excitotoxin that can product cellular excitation, cell death in the brain, it can alter the way the brain is formed in newborn babies that permanently changes the brain formation, results in behavioral changes in children, hyperactivity. The phenylalanine can also alter how the brain is formed during the fetal formation of the brain and thereafter, it can produce lowering of the seizure threshold so you're more likely to have a seizure. Phenylalanine and aspartic acid are both well recognized neurotoxins. So this combination by putting three relatively powerful neurotoxins into one combination is just to me unbelievable."
It's unbelievable that industry is so greedy it doesn't want to lose the profits from pregnant women using their poison even if it kills the baby. After 8 years we were able to find two studies FDA sealed, having to do with the Bressler Report. They were teratology studies and even showed cleft palate. They were so bad that FDA didn't want the public to know aspartame causes birth defects. http://www.mpwhi.com/fda_hid_research_that_damned_aspartame.htm Aspartame is a known abortifacient and teratogen. http://www.rense.com/general/asp.htm The Bressler Report is an FDA audit of several studies, and Jerome Bressler personally told me it has always bothered him that the studies were sealed, and pregnant women didn't have the facts that aspartame causes birth defects. Thanks to the Denmark Study here's an opportunity to at least get the birth defect warning and stop more birth defects and mental retardation, but EFSA doesn’t want to accept it. Dr. Louis Elsas, Pediatric Professor, Genetics, formerly Emory University testified before Congress it causes birth defects. Emory University has many of the studies. It doesn't take a rocket scientist to tell you two neurotoxins and an excitotoxin will cause birth defects.
“The European Environmental Association has projected that with the rise of autism caused by toxic foods like Aspartame, MSG, Fluoride, and environmental degradation, by 2013 no one will be born in the Western World that does not to some degree have autism. Dr. Bill Deagle’s board of AAEM, American Academy of Environmental Medicine and Dr. William Rae, director of the Dallas Environmental Clinic agreed in open discussion at the October 2010 annual meeting.” Bill Deagle, M.D. You also have Dr. John Harrison's chart showing autism soaring after the approval of aspartame. http://www.wnho.net/autism_chart.htm
You have already been sent Dr. John Olney's testimony before the Board of Inquiry as to how aspartame would destroy the brains of our children: http://www.wnho.net/dr_olney1.doc The prophecy has been fulfilled. At the time the FDA agreed with Dr. Olney and did revoke the petition for approval. Then Rumsfeld "called in his markers" as you know and aspartame was approved over the objections of the Board of Inquiry. You have already seen the Report For Schools: http://www.mpwhi.com/report_on_aspartame_and_children.htm Included is the ADD people's report, (Feingold} who has banned aspartame from their diets.
If a researcher is not willing to say aspartame is safe the aspartame industry won't fund it. Dr. Diana Dow Edwards was funded by Monsanto to study possible birth defects caused by the ingestion of aspartame. After preliminary data showed damaging information funding for the study was cut off. Yet a study with 60,000 people was not enough for EFSA to accept.
EFSA says regulatory agencies have all found aspartame safe. How would they know? Admittedly the aspartame industry has very strong ties to these agencies, and the agencies simply use the industry propaganda just as EFSA did. Other than using industry propaganda what else did they do? I spoke with Food Standards in New Zealand when I was there and was told they never did studies but relied on the FDA. We call that a rubber-stamp.
If EFSA wants to be believed they need to remove all industry generated misinformation on their web site. The site needs to show aspartame does get into the blood stream and the formaldehyde does accumulate. If you're not willing to remove false industry propaganda how could anyone take your review seriously?
EFSA's site states that the "Scientific Committee on Food (SCF) carried out a review of all original and more recent data on aspartame in 2002 and concluded that aspartame is safe for human consumption" We are missing the facts here as well. Felicity Mawson, (Mission Possible UK) and I were there and gave the EU all the damning information on aspartame. Most damning information was eliminated like all of Dr. Roberts work. Fortunately OLAF caught what was going on. “No committee made the decision, but only one person”. A flack with links to Ajinomoto?? His intentions are obvious and the so-called review was exposed and rebutted: http://www.holisticmed.com/aspartame/scf2002-response.htm
The EFSA site should reflect the facts not propaganda. This was no unbiased review, just another stab by industry to influence the outcome of a review. So SCF was dissolved and EFSA was born.
The track record of EFSA has continually been as Dr. Herman Koeter said before he resigned: "We were pressured by industry to hijack science."
Is it too much to ask, that EFSA eliminate the misinformation furnished to them by industry? The people have a right to get facts and protect their health. Otherwise no review can be taken seriously. Multitudes of deceived and uninformed victims are being sacrificed.
I found one of the missing pages from the Searle study which I sent you. It reveals differences relating to the DKP.
Dr. Betty Martini, D.Hum.
Founder, Mission Possible World Health International
9270 River Club Parkway
Duluth, Georgia 30097
Aspartame Toxicity Center: http://www.holisticmed.com/aspartame