Dr. Betty Martini, D.Hum.
Mission Possible World Health International
9270 River Club Parkway
Duluth, Georgia 30097
Telephone: 770-242-2599
E-Mail: BettyM19@mindspring.com

Posted: 25 June 2008

From: Dr. Betty Martini, D.Hum., Bettym19@mindspring.com
To: Commissioner@fda.gov, mitchell.cheeseman-fda.hhs.gov, laura.tarantino@fda.hhs.gov, LJAFFE@OC.FDA.GOV, mherndon@oc.fda.gov, michael.herndon@fda.hhs.gov, david.acheson@fda.hhs.gov, AskDOJ@USDOJ.GOV
Date: Tue, Jun 24, 2008 2:24 pm
Subject: Junk Science Carl Manion, (and Allen Edmundson) the man who recommended aspartame for pain and gave it to his MS suffering wife who died, is now going to make health care products with the poison to absorb into the skin. Publishes the use of aspartame for the very things it causes. Past reports below as well.

This is about as ludicrous as it gets. As you well know, aspartame triggers all types of rashes, rosacea and urticaria or hives big time. Now Manion is going to make skin products with this deadly poison.

Here is the article that came out about giving it to patients about pain: http://www.dorway.com/abc/index.html If you'll look at the FDA report of 92 symptoms you'll see how many types of pain aspartame causes from headache and joint pain to cardiac pain. http://www.mpwhi.com/92_aspartame_symptoms.pdfwww.mpwhi.com/92_aspartame_symptoms.pdf

If that wasn't bad enough here's how he wants to use it for sickle cell anemia patients which can easily die. http://www.wnho.net/aspartame_murdering_blacks.htm Murdering Blacks with Aspartame

As you may know Aspartame Triggers Most Blood Disorders from leukemia, idiopathic thrombocytopenic purpura, and lupus to anemia. http://www.rense.com/general70/aasp.htm

Has this man been told to help knock off the public with aspartame by telling people to use it for the very problems it causes?

Reports from the past:

Date: Thu, 28 Jun 2001 03:01:31 -0400 (What I wrote about this man in 2001)
From: Betty Martini
Subject: Manion Reveals Aspartame Swings Both Ways

For years FDA and aspartame producers declared its just a food additive, gets digested, never never never gets in the blood. And, of course, aspartame is NOT A DRUG, a pharmaceutical healing agent, say they!

Then C B Manion announced in l998 aspartame controls pain from arthritis. This won lots of media coverage, including a writeup in the illustrious peer-reviewed medical journal Clinical Pharmacology & Therapeutics l998; 63: 580 - 593: Treatment of Osteoarthritis With Aspartame. Since aspartame is well known to harden the synovial lubricating fluid in your joints, with excruciating results, Manion's revelation seemed odd at the least.

Finally the truth came out when Dr. H. J. Roberts ordered records of Manion's work: Guess what, there was only a single person in the "study": Manion! He drank some aspartame and said: "I'm better! Perhaps it was in a Rum and Diet Coke! Was it the Bacardi that did the work?

We're awed by this brilliant breakthru by Miracle Manion, and specifically call attention to the enormous benefits his revolutionary test protocol brings to medical science which has wasted trillions on double-blind studies on thousands of subjects to be sure drugs work on a population basis. No more that! Consider the terrific time economy from lab to market. When Joe chemist invents the next super popper potion for peptic petunias all he has to do is swig a shot, say he feels wonderful, and he's off to the hall of fame (via the bank).

Now comes Miracle Manion with even more stupendous breakthru (we knew he could do it again!) . His new studies show aspartame cures sickle cell anemia. Yep, he did it, right there in the lab, watched aspartame get in the blood and devour sickle cell; call the magazines!!

But what about the "never never never gets into the blood" proclamations? Well you see it's like this: Mondays, Wednesdays, and Fridays aspartame gets in your blood to cure sickle cell and dandruff, Tuesdays, Thursdays and Saturdays it gets digested because its not a drug and can't get in the blood.

So you ask, what about Sundays? Depends on the time of day, you see. Perhaps you're wondering how our marvelous rat poison makes these changes: Well it's under psychic control, er.. witchcraft. So stop asking all these fool questions and simply make One Shot Miracle Manion AMA man of the year for proving what we knew all along; aspartame gets in the blood!

ARE YOU LISTENING DR. HARRIS AT THE FDA? WHEN WILL YOU RECALL THIS VENOM? The FDA has approved a drug to be marketed as an additive. That, Dr. Harris, I'm afraid is against the law.

Read on for Dr. Manion's new study!

Betty Martini, Founder, Mission Possible International 770 242- 2599

Friday June 22 1:23 PM ET
Aspartame Possible Therapy for Sickle Cell Anemia
NEW YORK (Reuters Health)

The artificial sweetener aspartame could one day be used to treat the symptoms of sickle cell anemia, preliminary study findings suggest.The genetic mutation that causes sickle cell disease results in the production of a defective form of hemoglobin, the molecule red blood cells use to deliver oxygen to tissues throughout the body. The defect causes the red blood cells to take on a sickle shape, and makes them unable to deliver oxygen efficiently.

The sickled cells can block tiny blood vessels called capillaries, which is extremely painful and can lead to organ and tissue damage and stroke. Acutely painful episodes lasting hours or days in which the blood vessels are blocked and organs are damaged occur in 70% of sickle cell patients, according to the National Institutes of Health (news - web sites), and are called crises.

Aspartame has been shown to bind with two proteins that may block the formation of sickled cells, researchers explain in a recent issue of Clinical Pharmacology and Therapeutics.

To investigate, Dr. Carl V. Manion and colleagues from the University of Oklahoma Health Sciences Center in Oklahoma City conducted a study on sickled cells in test tubes and one in humans.

According to the test tube study of blood samples from 20 children with the disease, sickled cells decreased from 28% of all red blood cells to less than 14% when 1 milligram (mg) of aspartame was added to 1 milliliter (mL) of blood. Sickled cells decreased further when 2 mg aspartame was added.

Similarly, the researchers found a decrease in the number of sickled cells in 15 affected individuals who consumed aspartame.``In the presence of aspartame...the numbers of sickled cells were found to decrease significantly,'' Manion and colleagues write.

The findings warrant further investigation of aspartame for treating or preventing sickle cell crises, the researchers conclude.

``Aspartame is particularly convenient to use in clinical trials because it is considered to be safe for human consumption,'' they note.Sickle cell disease is most common in people of African descent. According to the National Institutes of Health, the disorder affects about 1 in 600 African Americans.

SOURCE: Clinical Pharmacology and Therapeutics 2001;69:346-355

Here is the letter when I originally reported this population destroyer: Date: Mon, 10 Jun 2002 18:48:42 -0400
To: jowens@osbmls.state.ok.us
From: Betty Martini, Bettym19@mindspring.com
Subject: Open Letter, Oklahoma State Licensure, Asking for Complete Investigation on Carl V. Manion, M.D., Oklahoma Medical Research Foundation. Title 18, Section 1001 states it is a crime to mislead the public Aspartame Disease Declared Global Plague

Dear Ms. Owens:

I'm reporting Dr. Carl V. Manion for his continuing efforts at misleading the public. Aspartame (NutraSweet/Equal/Spoonful, etc.) has been on the market for 20 years. Obviously it is well known that it is a deadly neurotoxin. First of all, the FDA did not want aspartame approved, they wanted Searle indicted for fraud. On January 10, l977 in a 33 page letter, FDA Chief Counsel Richard Merrill recommended to U.S. Attorney Sam Skinner that a grand jury investigate Searle for "apparent violations of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 331 (e), and the False Reports to the Government Act 18 U.S.C. 1001, for "their willful and knowing failure to make reports to the FDA required by the Act 21 U.S.C. 355 (i) and for concealing material facts and making false statements in reports of animal studies conducted to establish the safety of aspartame." The FDA called special attention to studies investigating the effect of NutraSweet on monkeys and hamsters.

The only reason Searle was not indicted was that both U.S. Prosecutors William Conlon and Sam Skinner hired on with the defense team and the Statute of Limitations Expired. There was constant refusal by the FDA to approve aspartame and finally Searle hired Don Rumsfeld, now Secretary of Defense who said he would call in his markers and get it approved anyway. You will find this documented in the Congressional Record and in the 8 month investigation by UPI which is on http://www.dorway.com The day after President Reagan took office he appointed an FDA Commissioner to approve aspartame, Dr. Arthur Hull Hayes. A Board of Inquiry was set up of the best scientists the FDA had to offer who said aspartame was never proven safe and triggered brain tumors, and the petition was revoked. But Dr. Hayes was there to approve aspartame and Ajinomoto came to the rescue, the aspartame manufacturer that Monsanto has now sold a part of NutraSweet. They told Hayes with their study on brain tumors he didn't have to worry about the issue, but their study showed brain tumors as well. Hayes acknowledged in his l981 decision that he had only consulted a preliminary report of the Japanese evaluation and only skimmed it. More serious Hayes violated federal law by basing approval on the test, as it had not been reviewed by the FDA board. He has refused to talk to the press ever since.

Once marketed the FDA was flooded with complaints and they wrote a report of 92 documented symptoms which you will find on http://www.dorway.com There were so many complaints as people suffered MS symptoms, seizures, psychiatric and behavioral problems, joint pain, headaches, birth defects, etc., that the Center for Disease Control was asked to investigate. They did the most damning investigation ever done and concluded that more neurological studies were needed. But they compromised their principles by adding a summary that contradicted the report and then sent out only the summary. The actual investigation we have on web. As victims began writing Congress about being poisoned Senator Howard Metzenbaum attempted to set up congressional hearings, but it was Senator Orrin Hatch who tried to prevent them. By l985 Searle was sold to Monsanto and hearings were held. But Hatch, paid by Monsanto, did a hatchet job so a moratorium was never put on aspartame and neither did the bill written by Senator Metzenbaum that would have required the National Institutes of Health to do studies on problems being seen in the population ever get out of committee. It was admitted in these hearings that the FDA was so flooded with complaints they were referring them to the AIDS Hotline.

By l986 so many people were going blind on aspartame and having seizures that the Community Nutrition Institute petitioned the FDA to ban aspartame but they refused. The FDA had done everything they could to prevent the approval of aspartame but once approved their loyalty with solely on the side of the industry. They were now guilty of malfeasance in the approval process.

Dr. James Bowen who sustained Lou Gehrigs disease from aspartame even wrote the FDA telling them that the marketing of aspartame was mass poisoning of the American public and more than 70+ plus countries of the world. You will see this letter regarding labeling on web. Today we are faced with what may be the largest plague in world history. Aspartame is a neurotoxic drug that interacts with just about every drug used to treat the problems it causes. For instance, it is a seizure triggering drug and interacts with Dilantin and like drugs. Used by diabetics it can actually precipitate diabetes, keeps blood sugar out of control, destroys the optic nerve and can cause diabetics to go into convulsions. It even interacts with insulin. It damages the cardiac conduction system and can cause sudden death, and interacts with cardiac Rx. The phenylalanine in aspartame lowers the seizure threshold and depletes serotonin. Lowered serotonin triggers psychiatric and behavioral problems, but aspartame interacts with antidepressants. It can trigger neurodegenerative diseases such as Parkinson's and interacts with L-dopa. It is now all completely documented in the new medical text on the global plague titled:

Aspartame Disease: An Ignored Epidemic, http://www.aspartameispoison.com or http://www.sunsentpress.com or 1-800-827-7991. H. J. Roberts, M.D.

Mission Possible is a worldwide volunteer force in 50 states and over 22 countries of the world warning all consumers off this deadly chemical poison. As neurosurgeon Russell Blaylock, M.D., (author of Excitotoxins: The Taste That Kills about aspartame, http://www.amazon.com) says in a lecture, you have to understand the reactions to aspartame are not allergic but toxic like arsenic and cyanide. to make matters worse aspartame is a chemical hypersensitization agent so victims react to other toxins and vaccines and even GM food. It is a teratogen triggering birth defects and an abortifacient causing miscarriages big time. It is notorious for its MS symptoms and for triggering lupus. Dr. Bowen in Aspartame Murders Infants on web explains that aspartame is an adjuvant and forms antigenic tissue. He says: "The ability of methyl alcohol/formaldehyde to create antigenicity, especially as combined in aspartame molecules is so great as to cause severe autoimmune reactions to the tissues deformed by formaldehyde polemerization, adduct formation. The immune system turns against the victim's tissues: Lupus." Aspartame completely destroys the central nervous system and mimics MS. Searle actually did studies in South America sacrificing people in poor villages to see how much aspartame a victim could take. These studies showed that aspartame destroyed the brain and central nervous system and hardens the synovial fluids accounting for the agonizing joint pain suffered by aspartame victims. Some people suffered seizures and some brain tumors. People died in the studies. The notarized affidavit of the translator, N. Vera is on web. Finding out that aspartame is a killer instead of publishing the studies Searle sold to Monsanto who has now sold to Ajinomoto, Child's in Boston, Michael Dell and a group of Monsanto managers who formed some sort of investment Company.

Today there are Aspartame Detoxification Centers in the US and even support groups on line to assist victims. (http://www.mpwhi.com, scroll down to banners) The Aspartame Toxicity Center recording the horror stories is http://www.holisticmed.com/aspartame We are now taking case histories for class action starting with brain tumors, seizures, eye problems and blindness.

In original studies aspartame triggered brain, mammary, uterine, ovarian, testicular, thyroid and pancreatic tumors for starters, and grand mal seizures. The late FDA toxicologist, Dr. Adrian Gross who tried so hard to prevent aspartame's approval told Congress that aspartame violated the Delaney Amendment because without a shadow of a doubt it can trigger brain tumors. His last words to Congress were "And if the FDA violates its own laws who is left to protect the public?" Dr. Jacqueline Verrett, the other on-site toxicologist told congress, that all studies were built on a foundation of sand and should be thrown out. And these studies approved this neurotoxin.

Now here comes Manion who has been doing "studies" on aspartame that should be framed in the Museum of Madness. His buddy, Edmundson drinks a diet soda (one person , one dose study) and says aspartame is good for joint pain!! Of course, a component of aspartame, methanol, is classified as a narcotic. (Louis, R. J. Sax's Dangerous Properties of Industrial Materials, Eighth Edition, New York, Van Nostrand Reinhold (1992) pp. 2251-2252 During prohibition as thousands of skid row drunks drank wood alcohol they went blind or died. I'm sure before they died "they felt no pain" but they went blind or died just the same. Joint pain is about 31 on the FDA report of 92 symptoms and you'll see many other "pains" associated with aspartame such as abdominal Pain (#5) and localized pain (#26). It also triggers carpal tunnel which was reported in Townsend Letter for Doctors. On http://www.dorway.com you will see Dr. H. J. Roberts position paper on aspartame and fibromyalgia and arthritis. Fibromyalgia is a diagnostic wastebucket. Because of industry and FDA propaganda on aspartame physicians do not correlate the joint pain with the culprit aspartame and many times call it fibromyalgia. Even physicians drink diet soda and use aspartame as Dr. Richard Sabates did and even as an MD could not diagnose himself. He went from physician to physician and even the Mayo Clinic but continued to suffer. One day he read Dr. Roberts article on aspartame and joint pain in Townsend and got off of it. His pain disappeared and he wrote a book, his first chapter My Aspartame Nightmare, thanking Dr. Roberts for saving his life. You will find this chapter with his permission on web. http://www.dorway.com which houses the records of Mission Possible International was set up by Dave Rietz, Mission Possible South Carolina. He suffered for 12 years with joint pain from aspartame and over 20 physicians could not help him. Finally he saw the FDA report on the Internet, saw joint pain and got off the toxin. His pain disappeared. He set up this web site he said to give back to the Internet what the Internet gave back to him, his life!

Recently, a study was done by the University of Florida showing that when you remove excitotoxins, aspartame and MSG, the symptoms of fibromyalgia and chronic fatigue syndrome disappear. Now Manion with his one person, one shot study has joint pain victims using the very toxin that may be causing their problem.

Dr. Manion was written by countless victims after this study and refused to answer. I gave him the web site which has government records and a river of information from physicians, as well as peer reviewed research. He cannot say he doesn't know.

Next Manion comes out with a study on aspartame and sickle cell anemia. It was so absurd I didn't know whether to laugh or weep for those he would mislead. Aspartame interacts with Coumadin as discussed in the medical text so when there was a class action on Coumadin which had been on the market for years and years I thought perhaps the victims were also using aspartame. They mentioned Manion's study so you see my letter attached explaining the facts.

If consumers use aspartame for years as it destroys the central nervous system it mimics MS. I see in Manion's comments that his wife with MS was using it and wonder if that is why she was diagnosed. To suggest for aspartame to be given to MS victims is like asking fireman to use gasoline to put out fires. On hearing of this report Dr. James Bowen called and said: "Post market surveillance is another name for the concept that the proof is in the pudding. This goes right along with Dr. Manion's admitted experience that he continued to poison his wife with aspartame and watched his wife worsen and eventually die of her disease. His mind is obviously too twisted to even observed simple facts of clinical experience and come to a rational conclusion. His wife died of the disease. He claims that this is prima facie evidence that aspartame is good for people with multiple sclerosis. How more incompetent and deranged could a man be. He would have to be both for that to appear to be a logical conclusion. "

"In every instance cited by Dr. Manion he admits to the noted correlation between aspartame consumption and various stated diseases. In every instance, he then disobeys the rules of science by trying to explain this away with fatuous punditry."

I have for years sent Dr. Bowen copies of cases of victims of aspartame disease who were misdiagnosed as having MS. Off aspartame some have gotten up out of wheelchairs and walked away. Dr. Bowen said: "You should request Dr. Manion give us a similar list of people who got out of their wheel chairs because they used aspartame or continued to use thereof. His late wife is obviously not an example."

What could happen if MS victims read this hogwash from Manion and took it seriously is seal their fate. Read the story of Joyce Wilson on web who used aspartame and was misdiagnosed as having MS. It was too late for her and she went blind and died. On the other hand, Alicia Morris who was diagnosed by two physician as having MS, got off aspartame and in 5 weeks all symptoms disappeared. Aspartame also changes the menses and causes infertility and she thought she could not have children. Several months later she got pregnant and gave birth to a baby boy. Ermelle Martinez, was ready for a wheelchair as she would trip when she would try to walk. She started using aspartame in medical school, was diagnosed as having MS and had to leave. Referred to us and off aspartame she is now 90% improved and Mission Possible Los Angeles. She can run and swim and no one would ever know she was diagnosed as having MS.

Why has the FDA had to review aspartame's safety 17 times in 21 years? Because of being flooded with complaints on aspartame and doctors and scientists screaming for recall of this toxin. Unfortunately, the FDA is solely on the side of industry today and Ed Horton of the prestigious Lancet wrote in May of last year that the FDA takes money from industry and endangers the lives of the people. Dr. Ralph Walton was on 60 Minutes with Dr. John Olney (founded the field of neuroscience called excitotoxicity) in l996 and showed his report which we have on web regarding peer reviewed research and funding. Only industry funded and controlled research ever said aspartame was safe. 92% of independent and unbiased peer review research shows the problems, and if you eliminate one pro-industry review and studies the FDA had something to do with, 100% of independent studies show the problems.

Dr. Russell Blaylock explains how studies are fixed in an interview with Mission Possible Radio, transcript on web. An example is the Rowan Study funded by Monsanto on aspartame and seizures. Knowing that aspartame is a seizure triggering study they set out to defend their product by doing a study. There were 18 people in the study but what they didn't tell you is that they gave 16 of them anti-seizure medication so they couldn't have a seizure. And the study lasted all of a study with each victim being given a capsule of aspartame. Tantamount to smelling the bottle! That's what we have to put up with because of the power of industry. And the manufacturer wouldn't have to stoop to doing such if their product was safe.

Dr. John Olney's curriculum vitae is on web. He is one of the most famous neuroscientists in the world today. He did the studies on aspartic acid which is 40% of aspartame and found it caused lesions in the brains of mice. This was in l970. He told Searle but they didn't tell the FDA until after it was approved. Aspartic acid is an excitotoxin.

Recent studies continue to show the problems. One in Norway a few months ago showed aspartame destroys the brain, especially in the area of learning accounting for the global epidemic of ADD. The Trocho Study shows the formaldehyde converted from the wood alcohol accumulates in the cells and damages DNA. Most toxicity is in the liver but substantial amounts in the kidneys, adipose tissue, retina and brain. So on top of all the horrors that aspartame triggers you also get embalmed, and there is a page on this in the medical text. Aspartame is also escalating Alzheimers (Defense Against Alzheimers Disease, http://www.sunsentpress.com) and memory loss is so common its #9 on the FDA list. Some victims say they have to write instructions to find their way home. And memory loss has been proven on a study in the last year or so. Headaches are so common it is #1 on the FDA report. MSG, another excitotoxin, has a synergistic effect with aspartame. http://www.truthinlabeling.org

This is why when the glutamate people even before aspartame was approved did a study on MSG they used aspartame as the placebo. Knowing MSG would react they said they would show it didn't react anymore than the placebo, so they had to find something they knew was excitotoxic, and this was even before approval. The FDA admitted this was wrong but until caught in their files said nothing. They had had those records of this crime for 20 years!!

Dr. Manion uses professional organizations like the American Dietetic Assoc to defend aspartame's safety but these organizations are funded by industry and have been written for years by experts on aspartame to stop pushing aspartame propaganda. The ADA are known as Monsanto's media flacks. Even the famed Dr. Julian Whitaker wrote an article some years ago titled The ADA Must Be Stopped In Their Tracks (Jan 1995) and the New York Times wrote Nov 15, 1995 "Corporate support to Dietitians Group Is Called Unhealthy. He even uses the American Council on Science and Health which is one of the worst front groups funded by Coke, National Soft Drink Association, Monsanto, NutraSweet and Searle. When I lectured for the World Environmental Conference in l995 and the email made world news this front group told the world it was all a hoax. Dr. Stephen Barrett is an advisor with this group and has a web site that protects the products of those who fund this organization. He even tries to tell people there is no such thing as multiple chemical sensitivity which is rampant in this nation, probably because of aspartame. His list is nothing but an advocacy group against alternative medicine. He has now been sued for violation of civil rights and racketeering. Doctors have written for years to the MS Society for trying to protect aspartame and my letter to them quoting Dr. Roberts medical text on MS is on http://www.dorway.com/nomarkle.html

Dr. Manion is probably scared now that the study on fibromyalgia was on TV just recently in Miami. For whatever reason Manion is pushing aspartame again his misinformation could cause the death of aspartame victims, especially those suffering with MS symptoms. He should be investigated and his ethics, credentials and mental stability examined. One should check out any funding from political action fronts and association with aspartame manufacturers, as well as perks.

We are now faced with what may be one of the largest plagues in world history. The last thing we need is comedians to mislead the public. Aspartame Disease is killing people and no one should consume it. There is no safe dose and in congress it was admitted that the Allowable Daily Intake was set for rats not humans. You can't set an allowable dose of a poison for humans. And remember aspartame breaks down to diketopiperazine, a brain tumor agent. Even on the biggest brain tumor list people keep questioning with so many people are suffering from brain tumors. That's because 2/3rds of the population is using a deadly neurotoxin that as FDA toxicologist, Dr. Adrian Gross, told Congress without a shadow of a doubt can produce brain tumors. Immediate action must be taken to prevent any more of this nonsense.

There are 100,000 web sites on aspartame, most warning consumers off of it. There is no way with all the letters written to Dr. Manion that he doesn't know what he is doing. And more and more medical books are written on it. Two more coming out this fall. According to Alex Constantine in NutraPoison aspartame was actually listed with the pentagon in an inventory of prospective biochemical warfare weapons submitted to Congress. The National Soft Drink Association protest, part of the congressional record, also on web, shows it breaks down at 86 degrees. Yet the pop companies sent it to the Persian Gulf with full knowledge to cook in the 120 degree Arabian sun. It would have also interacted with Anthrax vaccine. 40,000 have perished and a new study shows the Lou Gehrigs symtoms. As I told the government, aspartame destroys the central nervous system, mimics MS and causes Lou Gehrigs symptoms. One support group in Texas has 70 vets with brain tumors.

And now Dr. Blaylock says excitotoxins have destroyed the immune system of consumers so they could not even sustain chemical warfare. For this reason he has written a brochure to help those who have been consuming excitotoxins to save their life - http://www.bioterrorismbook.net Something must be done about Dr. Manion immediately before people begin to people him. The fact that he couldn't answer our letters shows he knows what he is doing. Read on for his remarks reported on Ivanhoe Newswire, and my letter to Dupont about his sickle cell anemia study.

The complete Board of Inquiry report telling the FDA not to approve aspartame, Dr. Olney's testimony to the Board of Inquiry and the l985 congressional record will be added to http://www.dorway.com within a few days showing the profound seriousness of this issue.


Mrs. Betty Martini
Founder, Mission Possible International
9270 River Club Parkway
Duluth, Georgia 30097

Note: This Oklahoma organization did absolutely nothing so they could continue to do more harm!

From: Betty Martini
Date: Mon, 15 Oct 2001 23:58:44 -0400
Letter to Gay K. Owens, Pharm.D., Dupont Pharmaceuticals Company - Coumadin and Aspartame Interaction

Gay K. Owens, Pharm.D.
Drug Information Specialist
Professional Services
Dupont Pharmaceuticals Company
Chestnut Run Plaza
974 Centre Road
Wilmington, Deleware 19805
Re: Coumadin's Interaction with Aspartame Your letter of October 11, 2001

Dear Ms. Owens:

Thank you for your letter. I contacted you because when I heard about the class action on Coumadin, I thought it was probably because the consumers were also using aspartame which interacts. Believe me, after 20 years on the market the reactions have become a part of many medical records. In fact, H. J. Roberts, M.D. has now declared Aspartame Disease to be a global plague and published a medical text titled Aspartame Disease: An Ignored Epidemic, http://www.aspartameispoison.com I am enclosing a brochure for the text which every pharmacy should have as there is a chapter on drug interaction and Coumadin is discussed. As the test brings out the likelihood of interference by aspartame was raised in patients who had been maintained on coumarin for extended periods, without difficulty. Unexpectedly, their prothrombin times approximated the control values (meaning a loss of anticoagulant effect), coupled with recurrent thrombophlebitis or angina pectoris.

I'm quite familiar with the comedians A. B. Edmundson and C. B. Manion. They even did a study on the treatment of osteoarthritis with aspartame - Clinical Pharmacology and Therapeutics 1998, 63, 580-593. In this case Edmundson drank a diet drink and said he felt better. Would you believe this was a one person study, and the one person was Edmundson who drank a diet soda. And this was published in prestigious medical journals and magazines everywhere as if there was a true, valid study. In reality, aspartame hardens the synovial fluids and causes agonizing joint pain often diagnosed as fibromyalgia (a diagnostic wastebucket). There was a study that showed this in South America but since it also showed aspartame to be a killer, Searle decided not to publish the studies.

The Edmundson/Manion study you are quoting here was also highly amusing. Their claim to show either a possible therapeutic or curative relationship between the ingestion of aspartame and sickle cell anemia disease presents several serious flaws. One is that he dose used in the test tube is at least hundreds of times more than the dose that would reach the body using NutraSweet unless you consider that only an insignificant amount of aspartame is absorbed into the blood stream intact - in which case that would be thousands of times greater in the test tube. Secondly, the mere dropping of the sickle cell count in the blood would more than likely indicate an increase in the severity of the disease because there is no known activity of aspartame that would suppress the formation of sickle cells. Therefore, the conclusion would be that more sickle cells would be sequestered at disease sites thus worsening the disease and the damages. It would be obvious to any experienced clinician that before any so-called scientist could make such irresponsible declarations about aspartame having a potentially curative or beneficial effect on sickle cell anemia, that it would be necessary to do an extensive open study both retrospective and prospective on the experiences of sickle cell patients who ingest aspartame.

Regardless of Dr. Manion's lack of understanding of aspartame it has proven one thing to the world and that is that aspartame is a drug and gets in the blood stream. This itself is reason for recall of aspartame. And the fact aspartame gets in the blood stream has always been documented, even in industry's own book - Aspartame, Physiology and Biochemistry, Marcel Dekker, Inc., New York, L..D. Stegink and L. J. Filer, Jr. l984. This is a pro-industry book and yet on page 161 you can read TISSUE DISTRIBUTION OF ORALLY ADMINISTERED ISOTOPICALLY LABELED ASPARTAME IN THE RAT. Yoshimasa Metsuzawa and Yuichi O'Hara, Life Science Laboratory, Central Research Laboratories, Ajinomoto Company, Inc. Yokohama, Japan. The results are on page 162 and show beyond any shadow of a doubt that aspartame gets in the blood.

Aspartame was approved as an additive and, by law, must be inert. As you see, aspartame is not inert, is a drug that interacts with other drugs, and it also changes brain chemistry. Unfortunately, the FDA serves above the law and disregards all evidence on the dangers of aspartame. They merely lie and deny. So it will take the courts to get this deadly neurotoxin off the market. But if you don't want more class actions on your drugs, I would suggest that you add "do not use this drug with aspartame". And that goes for any of your other drugs as well, as aspartame interacts with so many things such as L-dopa, Dilaudid, Dilantin, Premarin, anti-depressants, cardiac Rx, insulin and on and on.

As far as the class action on Coumadin is concerned, we would appreciate it, if you would ask all subjects if they were consuming aspartame at the time they were using Coumadin. Aspartame is also hidden in restaurant foods and artificial and natural flavors at times. It is very hard to avoid. See the FDA report attached of 92 documented symptoms triggered by this neurotoxin.

Aspartame also breaks down to diketopiperazine, a brain tumor and triggered astrocytomas and pituitary adenomas, etc. in original studies. The Trocho Study has shown that the formaldehyde accumulates in the cells (converted from the methanol) and damages DNA. When you damage DNA you can destroy the human race. Take this very seriously and add warnings on your products. Unfortunately the manufacturer and the FDA continue to lie and deny about this product, and there is nothing more despicable than a liar. And because of this people are sick and dying the world over. As you will notice from the medical text, aspartame triggers neurodegenerative diseases and all kinds of tumors and drug interactions. Take it seriously. More information on http://www.dorway.com There are also four support groups on line and 5 aspartame detoxification centers in the US, one in Canada.


Dr. Betty Martini, D.Hum.
Founder, Mission Possible World Health International
9270 River Club Parkway
Duluth, Georgia 30097
E-Mail: BettyM19@mindspring.com

Aspartame Toxicity Center: http://www.holisticmed.com/aspartame

Aspartame Documentary on how it has poisoned the world: Sweet Misery: A Poisoned World, http://www.soundandfury.tv

Date: Mon, 10 Jun 2002 12:52:55 -0400 Subject: Ivanhoe's Medical Breakthroughs - Aspartame A Different Perspective

Reported June 10, 2002

Aspartame: A Different Perspective

By: Sheila Sobell

(Ivanhoe Newswire) -- Internist Carl V. Manion M.D., is sweet on aspartame. Along with critics who claim the food additive triggers a variety of disorders from brain tumors to systemic lupus, he's convinced that the sweetener actually does cross the blood barrier into cellular structures. But that's where the similarities end.

"While our work has shown that aspartame 'does do something' to the body, the difference is that we think its effects are laudatory, not negative," he says.

A researcher at the Oklahoma Medical Research Foundation (OMRF), the third leading holder of medical patents, Manion feels so strongly about aspartame's analgesic properties that he prescribes it for multiple sclerosis patients. He even used it to ease his wife's suffering when she was dying of the disease.

"My wife had MS long before I became interested in aspartame," he says. "We only started using it in 1994 when scientists suggested it interferes with the production of antibodies, which could be beneficial in treating an autoimmune disease like MS. My wife said that nothing was as good as the aspartame in relieving head and joint pain and making her comfortable."

Currently Manion's group has applied for several patents resulting from their studies demonstrating that aspartame is "especially effective in relieving pain associated with osteoarthritis, multiple sclerosis, and sickle cell anemia."

New theories also suggest that aspartame might even help ward off testicular cancer.

If cancer researcher Gary G. Schwartz, M.P.H., Ph.D., of Wake Forest University is correct in hypothesizing that testicular cancer is triggered by a multi-step process beginning in pregnancy or early childhood with exposure to mold-contaminated grain, coffee, or pork, aspartame's biochemistry might be a key to its prevention. That's because aspartame's molecular structure is very similar to the mold toxin, ochratoxin A, and can prevent it from binding onto protein, thereby immunizing the animal (and hopefully people) against its effects.

Why then has aspartame gotten such a bad rap? Ivanhoe asked Dr. Manion to help clarify long-standing issues about aspartame's safety like whether or not it causes brain tumors.

"There isn't any doubt that a transient increase in the number of brain tumors was observed for a short time after aspartame's introduction," says Manion. "This fits with the fact that aspartame is an aspirin-like compound, which would have masked early symptoms of brain tumors like headaches. When the effects wore off [and the headaches returned], more patients consulted doctors and more tumors were diagnosed."

Interestingly, the downward fluctuation in tumor incidence didn't generate safety concerns, Manion points out. "Instead, everyone focused on the slight increase, overlooking the fact that the brain tumor rate balanced out within two years. Even regulatory bodies like the Food and Drug Administration (FDA) and the Centers for Disease Control (CDC) found no connection between aspartame and brain tumors."

Is aspartame implicated in Epstein Barr disease?

"At OMRF, scientists are collecting information to prove that Epstein Barr is a virus that's the root cause of lupus," says Manion. "Obviously, aspartame doesn't cause that virus, though change in usage patterns may trigger an immune system backlash. For example, suppose you have the virus in your body and don't feel well. Then you start taking aspartame and seem better. But when you stop the aspartame and its aspirin-like effects wear off, you feel worse. Does that mean aspartame caused the disease? No. Without aspartame, the disease, which was already there, just became easier to see."

Can using aspartame trigger depression and mood disorders?

"I haven't made those observations in people taking aspartame, but on the other hand I have seen how giving young children too much sugar makes them giddy and hyperactive," says Manion. "It's possible in my mind that big doses of aspartame might have an impact on sensitive individuals."

Dietary sensitivities and allergies might also explain why eliminating additives like aspartame and MSG could alleviate pain associated with fibromyalgia. Nonetheless, institutions like the American Academy of Pediatrics, the American Medical Association, American Cancer Society, American Dietetic Association, and the American Council on Science and Health stand behind its safety.

Do users develop "aspartame disease" resulting from methanol poisoning expressed by MS-like symptoms of depression, slurred speech, memory loss, and heart palpitations?

The term "aspartame disease" troubles Dr. Manion. He describes the problem in the following way: "Medicine has described a 'disease' as a process that satisfies 'Koch's postulate' which begins with symptoms, moves to observable findings in the body, and then defines a cause. The process is then reversed so that the proposed causal agent is given; the bodily changes are observed, and the symptoms follow.

"But this logical progression is badly flawed when it comes to aspartame disease. Not everyone experiences symptoms; no specific organ damage can be defined reproducibly, and any damages evaluated may be explained by numerous causes other than the aspartame. The rigor and thoroughness of Koch's postulate has not been something the aspartame disease advocates have been willing to follow, challenge, nor demonstrate."

"The FDA has reviewed data about aspartame's safety 17 times since it came on the market 21 years ago," says Daniel L. Azarnoff, M.D., who was president of research and development at Searle & Co. when it introduced aspartame. "The conclusion still is that it's safe."

Award-winning journalist Sheila Sobell (http://www.writersobell.com) is the author of three health books.

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Date: Thu, 09 Sep 2004 22:04:42 -0500
Subject: Aspartame and Population Control

The patent on aspartame held by Searle expired in December of 1992, allowing other companies besides the NutraSweet Company to produce aspartame (Therrien 42). NutraSweet Co. and G. D. Searle are divisions of the Monsanto Company.

In 1985 Monsanto purchased G.D. Searle, the chemical company that held the patent to aspartame, the active ingredient in NutraSweet. Monsanto was apparently untroubled by aspartame's clouded past, including a 1980 FDA Board of Inquiry, comprised of three independent scientists, which confirmed that it "might induce brain tumors."

The use of genetic engineering to make aspartame has stayed secret until now because there is no modified DNA in the finished product. Monsanto, the pioneering GM food giant, which makes aspartame, insists that it is completely safe. But some scientists fear that not enough is known about the process of making it. One of the two elements that make up the sweetener can be produced by genetically engineered bacteria, and scientists say that they cannot rule out toxic side-effects.

Breaking News From Dr. Betty Martini

The Oklahoma Medical Research Foundation, OMRF has http://www.omrf.org/OMRF/Admin/TechTransfer/Manion.asp patents on aspartame from 6 nations as an analgesic for headaches and other discomforts! Aspartame is supposedly a diet sweetener, keeps you slim. OMRF has patented it for appetite enhancement. It keeps you thin by making you crave carbohydrates, as we explained 12 years ago:

If you want to be fat, NutraSweet is where its at!

Every step in the human fertility cycle is destroyed by aspartame...It liberates free methyl alcohol. Damages the cardiac conduction system causing sudden death.

This neurotoxic drug triggers birth defects, learning problems, and behavioral problems. It interacts with all antidepressants, insulin, all cardiac Rx, anti-seizure Rx, hormones and L-dopa, for starters. As a chemical hypersensitization agent it even interacts with vaccines and other toxins. It has an additive and synergistic effect with MSG... - http://www.congregator.net/medicalnews/martini40909.html

A History Timeline of Population Control

"...Humanity must drastically scale down its industrial activities on Earth, change its consumption lifestyles, stabilize and then reduce the size of the human population by humane means, and protect and restore wild ecosystems and the remaining wildlife on the planet." - from an outline of a Government Project: The Wildlands Project

This website chronicles the timeline of mass killing from he Tartars infecting the enemy by catapulting bodies infected with bubonic plague over the walls of the city of Kaffa, to 1997 and Nobel Prize winner Dr Stanley Prusiner from the University of California, and the discovery of the role of molecules known as "prions" in the invariably fatal brain illnesses such as "mad cow disease" or bovine spongiform ecncephalopathy (BSE) in cattle, and Creutzfeldt-Jakob disease (CJD) in humans. - http://www.geocities.com/lord_visionary/populationcontrolagenda2.htm

This information is posted at: http://www.etherzone.com/forum/index.php?topic=1112.msg12722#msg12722

Bobby Garner http://www.congregator.net


Now you have the past reports as well as what Manion and Edmundson are up to at the current time. Some action must be taken, and aspartame must be banned immediately. A petition to ban six years ago has still not been answered by the FDA even though the law states that they only have 180 days to answer. An Imminent Health Hazard amendment was sent in October which they must answer in a week or so. Since FDA refuses to serve within the law their doors should be closed forever and the agency replaced with one with concern for safe food and drugs. More people today die from prescription drugs than illegal drugs as discussed recently in the New York Times. They have betrayed the public trust and responsible for unsafe food and drugs, and have given their loyalty to Big Pharma.

Please forward widely. We need big time help to stop these junk scientists spreading more addictive excitoneurotoxic carcinogenic aspartame to be used for the very things this poison causes. They must be stopped immediately.

Dr. Betty Martini, D.Hum.
Founder, Mission Possible World Health International
9270 River Club Parkway
Duluth, Georgia 30097
E-Mail: BettyM19@mindspring.com

Aspartame Toxicity Center: http://www.holisticmed.com/aspartame

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